Pengaruh Pemberian Ekstrak Etanol Kelopak Bunga Rosella (Hibiscus sabdariffa, L) Terhadap Kadar LDL Pada Mencit Putih Betina
Sari
Research on the effect of roselle calyx ethanol extract (Hibiscus sabdariffa Linn) on the levels of LDL female white mice have been done. The extract was administered orally with a variety doses 500, 700 and 1000 mg /kg bw once daily for 7, 14 and 21 days. as a negative control group using white female mice were given standard diet, while the positive control were given atherogenic cocktail as induction . The results showed that the ethanol extract of roselle calyx apparently have a significant effect on levels of LDL blood cholesterol of female white mice. dose of 28 mg/20 g bw showed reduced blood levels of LDL cholesterol better than a dose of 14 mg/20g bw and 19.6/20g bw. Based on further test duncan, reduced levels of LDL cholesterol on day 21 showed excellent results compared to most day 7th and 14th.
Teks Lengkap:
PDF (English)Referensi
Cheppy, S., 2005, Pembibitan Tanaman Obat, Penebar Swadaya, Jakarta.
Effendi, H., 2008, Uji Aktivitas Anti Asam Urat Ekstrak Calyx Rosella (Hibiscus sabdariffa Linn.) terhadap Mencit Putih Jantan (Skripsi), Universitas Andalas, Padang.
Emma, S., 2004, Buah dan Sayur Untuk Terapi, Cetakan 10, Penebar Swadaya, Jakarta.
Faraji M., and H. Tarkhani A., 1999, The Effect of Sour Tea (Hibiscus sabdariffa) on Essential Hypertension. Journal of Ethnopharmacology. 231-236.
Harbone, J., B., 1994, The Flavonoid Advance and Research Since 1968, Department of Botany, School of Plant Sciences, The University of Reading, UK.
Herty, M., dan Kristiana Lusi, 2005, Khasiat dan Manfaat Rosela, Cetakan I, Agomedia Pustaka, Jakarta.
Kaplan, A., 1999, Clinical Chemistry Interpreatation and Tecniques, LeaFebiger, Phyladelphia.
Mardiah, 2009. Budi Daya dan Pengolahan Rosella, Cetakan I, Agomedia Pustaka, Jakarta.
Olaleye, M. Tolulope, 2007, Cytotoxicity and Bacterial Activity of Methanolic Extract of Hibiscus sabdariffa. Journal of Medicinal Plants Research. 009-013.
Susanti, D. 2009. Pengaruh pemberian eksstrak etanol calix rosella terhadap kadar HDL dan kolesterol total pada mencit putih jantan (Skripsi). Stifi, Padang.
Thompson, E.B., 1985, Drug bioscreening : Fundamental of drug evaluation techniques in pharmacology, Gaceway Publishing Company Inc, New York.
Vogel, Gerhard. 2002. Drug Discovery and Evaluation Pharmacological Assays, Springer, Gemany.
DOI: http://dx.doi.org/10.52689/higea.v2i2.15
Refbacks
- Saat ini tidak ada refbacks.
##submission.license.cc.by-nc-sa4.footer##