Pengaruh Ekstrak Daun Jati (Tectona grandis L.f) Terhadap Fungsi Hati Dan Fungsi Ginjal Pada Mencit Putih Jantan

Elisma Elisma, Novi Priyoka Putra, Helmi Arifin

Sari


Study about sub acute toxicity of jati leaf extract toward white male mice has been done, which consist of SGPT activity for liver function test, creatinine clearance for kidney function test and organ’s weight ratio. The extract was administered orally once a day for 15, 30 and 45 days with variable dose of 150, 300 and 600 mg per kg body weight. The result showed that there were no significant effect of jati leaf extract administration to the SGPT activity, kidney function and organ’s weight ratio (p > 0.05).

Kata Kunci


Tectona grandis L.f; SGPT activity; creatinine clearance; organ weight ratio

Teks Lengkap:

PDF (English)

Referensi


Dalimartha, S., 2006, Atlas Tumbuhan Obat Indonesia, Jilid 4, Jakarta: Puspa Swara.

Departemen Kesehatan Republik Indonesia, 2000, Parameter standar umum ekstrak tumbuhan obat, Jakarta: Departemen Kesehatan Republik Indonesia Dir Jen POM.

Dirjen POM., 1996, Kumpulan peraturan perundang-undangan bidang sediaan farmasi, makanan, alat kesehatan, dan bahan berbahaya (Umum), Jakarta: Departemen Kesehatan RI.

Hartati, S., 2005, Detail penelitian obat bahan alam,Skripsi, Bandung: Sekolah Farmasi Institut Teknologi Bandung.

Jamaludin., 2008, Efek antidiare ekstrak etanol daun jati (Tectona grandis L.f) pada mencit putih jantan, Tesis, Surakarta: Universitas Muhammadiyah.

Jones, D.S., 2010, Statistika farmasi. Penerjemah: H. Rivai, Jakarta: Penerbit EGC.

Kaplan, A. and Szabo, L.L., 1979, Clinical Chemistry, Interpretation and Techniques, London : Henry kimpton publishers.

Newman, D.J., Price, C.P, 1999, Renal Function and Nitrogen Metabolites, Tietz textbook of Clinical Chemistery ,3nd ed, Philadelphia : Saunder Company.

Swandari, S., 2004, Uji aktivitas antidiabetes ekstrak etanol daun jati, Skripsi, Bandung: Dept. Farmasi Institut Teknelogi Bandung.

Thomson, E., 1985, Drug and bioscreening fundamentals of drugs evaluation technique in pharmacology, New York: Graceway Publishing Company.

Tjitrosoepomo, G., 1994, Taksonomi tumbuhan, Yogyakarta: Gadjah Mada University Press.


Refbacks

  • Saat ini tidak ada refbacks.


##submission.license.cc.by-nc-sa4.footer##