Pengaruh Pemberian Ekstrak Etanol Daun Patikan Kebo (Euphorbia Hirta L.) Terhadap Kadar Ldl Pada Mencit Putih Jantan

Surya Dharma, Hendri Fatriona, Elisma Elisma

Sari


Study about the influence of Euphorbia hirta L. leaves’s aethanolic extract on the levels of blood LDL in white male mice has been done. The aethanolic extract of Euphorbia hirta L. was given orally once a day for 7 th, 14 th and 21 th days.The doses used were 2, 6, 18 mg/ 20g body weight respectively. Control group was given standard food. Parameter was measured level of blood LDL. The result show that the aethanolic extract of Euphorbia hirta L. does not influence to the levels of LDL, while the time factor for 7 th, 14 th and 21 th days showed a significant effect (p <0.05).

Kata Kunci


Euphorbia hirta L. leaves’s aethanolic extract; LDL mice.

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Referensi


Chitra, M., Muga, V., Sasikumar, D., Awdah, M.A. (2011). Screening of phytochemical and in vitro activity of Euphorbia hirta L. J. chem. Pharm. Res. Vol 3, No. 6. 110-114.

Departemen Kesehatan RI. (2008). Farmakope Herbal Indonesia (Edisi I). Jakarta: Departemen Kesehatan Republik Indonesia.

Ganiswara, G. S. (1995). Farmakologi dan terapi. (Edisi IV). Jakarta: Bagian Farmakologi, Fakultas Kedokteran, Universitas Indonesia.

Ibrahim T. A., Adetuyi F. O., Ajala L. (2012). Phytochemical screening and antibacterial activity of sida acuta and Euphorbia hirta. Journal of applied phytotechnology in enviromental sanitation. Vol. 1, No.3. 113-119.

Jones, D. J. (2008). Statistika farmasi. Penerjemah Harrizul Rivai. Jakarta: penerbit EGC.

Jones, P. J., Sarjaz, M. R., Ntanios, F. Y., Vanstone, C. A., Feng, J. Y., Parsons, W. E. (2000). Modulation of plasma lipid levels and cholesterol kinetics by phytosterol versus phytostanol esters. J. Lipid Research. Vol 41. 697-705.

Kementerian Kesehatan RI. (2011). Suplemen II Farmakope Herbal Indonesia. (Edisi I). Jakarta : Kementerian Kesehatan Republik Indonesia.

Murray, R. K., Granner D. K., Mayes, P. A., & Rodwell V. W. (2003). Biokimia harper. (Edisi ke-25). Diterjemahkan oleh A. Hartono. Jakarta: Penerbit Buku Kedokteran EGC.

Price, S. A., & Lorraine M. W. (2000). Patofisiologi konsep klinis proses-proses penyakit. Edisi 6. Diterjemahkan oleh Hartanto dkk. Jakarta : Penerbit Buku Kedokteran EGC.

Rhasid, A. N. M. M., Shohel, M., Nayeem Md. T., Monokesh K S. (2013). A Compendium ethnopharmaceutical riview on Euphorbia hirta L. Ayupharm Int J Ayur Alli Sci, Vo. 2, N0.2, 14-21.

Sandeep, B. P., Chandrakant, S.M. (2011). Phytochemical investigation and antitumor activity of Euphorbia hirta L. European J Exp Biol, Vol. 1, No.1, 51-56.

Sandeep, B. P., Nilofar, S. N., Chandrakant, S. M. (2009). Review on phytochemistry and pharmacological aspect of Euphorbia hirta Linn. JPRHC. Vol. 1, No. 1, 113-133.

Sharma, N. K., Prasad R. (2008). Oxidative injury to protein and their protection by phenolic acid antioxidant from Euphorbia hirta leaves abstract. J. Biotechnol, Vol 136, 717-742.

Shirish, S. P. (2013). Evaluation of acute toxicity study for Euphorbia hirta L. Int J Bioassay. Vol.2, No 1, 329-332.




DOI: http://dx.doi.org/10.52689/higea.v5i2.90

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