Pengaruh Pemberian Jus Buah Labu Kuning Cucurbita moschata (Duch.) Poir. Terhadap Tukak Lambung Tikus Putih Betina Yang Diinduksi Dengan Etanol Absolut

Suhatri Suhatri, Relly Sapta Rahmat Hura, Elisma Elisma

Sari


The effect of the pumkin juice Cucurbita moschata (Duch.) Poir. on the ulcer of white female rat  induced by absolut ethanol was investigated using oral method. With The reseveral doses 0.4 ; 0.8 ; and 1.6 ml/200 g body weight doses. The result showed that the juice with 0,4, 0,8, and 1,6 ml/200 g body weight dose were able to cure the ulcer with curative ratio for each rasio dose are 22.22 %, 52.89 % and 71.04 %. It’s shows that higher dose give better result. The juice can also significantly decrease the gastric pH of rat induced by ethanol absolut to it’s normal value (P<0,05).

Kata Kunci


Cucurbita moschata; ulcus peptikum; gastric pH.

Teks Lengkap:

PDF (English)

Referensi


Mutchler, E., 1991, Dinamika Obat, Edisi V Bandung : Penerbit ITB,.

Julius,1992, Patogenesis Tukak Peptik, Cermin Dunia Kedokteran, Vol. 72.

Khazaei, M., and Hossein Salehi., 2006, “Protective Effect of Falcaria vulgaris Extract on Ethanol Induced Gastric Ulcer in Ratâ€, Iranian Journal Of Pharmcology and Therapeutics.Vol. 5, No. 1, hal 43-46

Siemonsma, and Kasem, P.J.S., 1994, Vegetables, Plant Resources of South-East Asia, No 8, Prosea, Indonesia, Bogor.

Syarif, A., Setiawati, A., 2007, Farmakologi dan Terapi, Edisi V, Jakarta : Penerbit Fakultas Kedokteran Indonesia.

Vogel, H. G., 2002, Drug Discovery and Evaluation Pharmacological Assays, 2nd ed., Germany : Springer-Verlag Berlin Heidelberg.

Wilson, L.P, and Price, S,A., 1992, Lambung dan Duodenum dalam Sylvia A.P., L.M. Wilson, Patofisiologi : Konsep Klinis Proses-Proses Penyakit, Edisi 4, diterjemahkan oleh dr. Brahmu pendit, Jakarta : Penerbit Buku Kedokteram EGC

Zhen, L. S., 2005, Ben Cao Gang Mu, China :The Time Literature & Art Press.




DOI: http://dx.doi.org/10.52689/higea.v3i2.53

Refbacks

  • Saat ini tidak ada refbacks.


##submission.license.cc.by-nc-sa4.footer##